Melanophilin (MLPH)

l1Rk3; l(1)-3Rk; Slac-2a; ln; Exophilin-3; Slp homolog lacking C2 domains a; Synaptotagmin-like protein 2a
Melanophilin (MLPH)
Melanophilin encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin.
A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Organism species: Homo sapiens (Human)
  • Protein RPH637Hu01Recombinant Melanophilin (MLPH)Customize
  • AntibodyPAH637Hu01Polyclonal Antibody to Melanophilin (MLPH)Customize
  • AntibodyMAH637Hu21Monoclonal Antibody to Melanophilin (MLPH)Customize
  • Assay KitSEH637HuELISA Kit for Melanophilin (MLPH)Customize
  • Assay KitSCH637HuCLIA Kit for Melanophilin (MLPH)Customize
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
  • Protein RPH637Ra01Recombinant Melanophilin (MLPH)Customize
  • AntibodyPAH637Ra01Polyclonal Antibody to Melanophilin (MLPH)Customize
  • AntibodyMAH637Ra21Monoclonal Antibody to Melanophilin (MLPH)Customize
  • Assay KitSEH637RaELISA Kit for Melanophilin (MLPH)Customize
  • Assay KitSCH637RaCLIA Kit for Melanophilin (MLPH)Customize
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