Methyltransferase 5 Domain Containing Protein 1 (METT5D1)

METT5D1, Belongs to the methyltransferase superfamily. RsmH family.Probable S-adenosyl-L-methionine-dependent methyltransferase.

Six genes were selected on the basis of their hypoacetylated status (MTA3, HDAC1, ATRX, MBD2, MBD3, and METT5D1), whereas the remaining genes were identified because of promoter hyperacetylation (NAB2, TMF1, BRMS1L, BCAR3, CYP1B1, GADD45B, and BAX). Five of the six chosen hypoacetylated targets are genes with roles related to chromatin remodeling or are involved in transcriptional repression, whereas the sixth (METT5D1) encodes a novel, uncharacterized transcript that possesses a putative methyltransferase domain.