Mitochondrial Ribosomal Protein S34 (MRPS34)

MRPS34 encodes a 28S subunit protein. Alternate splice variants of this gene have been described but their full-length nature has not been determined.

The deduced protein contains 218 amino acids. MRPS34 protein has a calculated molecular mass of 25.7 kD. Removal of a predicted N-terminal 18-amino acid mitochondrial localization signal results in a mature 23.6-kD protein. O'Brien et al. (2000) also identified a possible splice variant of MRPS34. O'Brien et al. (2000) and Koc et al. (2001) identified MRPS34 orthologs in mouse, rat, Drosophila, and C. elegans, but not in yeast or E. coli. Koc et al. (2001) reported that mouse and human MRPS34 share 86.5% amino acid identity.