Cholecystitis

Gallbladder Inflammation

Cholecystitis

Cholecystitis is inflammation of the gallbladder. Although most people with gallstones do not have symptoms and will not go on to develop cholecystitis, cholecystitis occurs most commonly due to blockage of the cystic duct with cholelithiasis. This blockage causes a buildup of bile in the gallbladder and increased pressure within the gallbladder, leading to right upper abdominal pain. 

The animal models for cholecystitis play irreplaceable and vital role in studying the etiology of cholecystitis, exploring its pathogeny and evaluating its treatment measures. The etiopathogenisis of cholecystitis is associated with many factors such as infection, hormone, nerve, metabolism etc. Following simulation clinical bacterium infection models, the application of common duct ligation, vagus nerve excision, food feeding, foreign matter implantation, drug inducing, and stenosis stone formation help to establish a lot of animal models which can simulate the corresponding cholecystitis.

Organism species: Mus musculus (Mouse)

Organism species: Rattus norvegicus (Rat)

Organism species: Cavia (Guinea pig )

Organism species: Oryctolagus cuniculus (Rabbit)

Organism species: Canis familiaris; Canine (Dog)