NADH Dehydrogenase Ubiquinone 1 Beta Subcomplex 5 (NDUFb5)

NDUFb5 is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Mammalian complex I has been studied extensively in Bos taurus. The names of some the bovine complex I subunits designate the single-letter code for the 4 N-terminal amino acids. The names of subunits B8-B22 designate their molecular weights.