NK2 Homeobox Protein 3 (NKX2-3)

NKX2C; NKX2.3; CSX3; NKX4-3; NK2 Transcription Factor Related Protein, Locus 3; Homeobox protein NK-2 homolog C
NK2 Homeobox Protein 3 (NKX2-3)
NKX2-3 is a member of the NKX family of homeodomain-containing transcription factors, which are implicated in many aspects of cell type specification and maintenance of differentiated tissue functions.Nkx2.3 contains a homeobox, a conserved NK2 domain, a C-terminal GIRAW motif typical of NKX2 proteins, and an N-terminal homology domain conserved among NK2 genes. RT-PCR and whole-mount in situ hybridization analyses detected Nkx2.3 expression primarily in gut mesoderm, distinct regions of the branchial arches, the tongue epithelium, and limited domains in the developing jaws, possibly including tooth anlagen.Nkx2.3 deficiency resulted in severe morphologic alterations in gut and spleen with early postnatal lethality in the majority of homozygous mutants.
Organism species: Homo sapiens (Human)
  • Protein RPP836Hu01Recombinant NK2 Homeobox Protein 3 (NKX2-3)Customize
  • AntibodyPAP836Hu01Polyclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Customize
  • AntibodyMAP836Hu21Monoclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Customize
  • Assay KitSEP836HuELISA Kit for NK2 Homeobox Protein 3 (NKX2-3)Customize
  • Assay KitSCP836HuCLIA Kit for NK2 Homeobox Protein 3 (NKX2-3)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPP836Mu01Recombinant NK2 Homeobox Protein 3 (NKX2-3)Customize
  • AntibodyPAP836Mu01Polyclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Customize
  • AntibodyMAP836Mu21Monoclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Customize
  • Assay KitSEP836MuELISA Kit for NK2 Homeobox Protein 3 (NKX2-3)Customize
  • Assay KitSCP836MuCLIA Kit for NK2 Homeobox Protein 3 (NKX2-3)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPP836Ra01Recombinant NK2 Homeobox Protein 3 (NKX2-3)Customize
  • AntibodyPAP836Ra01Polyclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Customize
  • AntibodyMAP836Ra21Monoclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Customize
  • Assay KitSEP836RaELISA Kit for NK2 Homeobox Protein 3 (NKX2-3)Customize
  • Assay KitSCP836RaCLIA Kit for NK2 Homeobox Protein 3 (NKX2-3)Customize
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