Home  |   About us
ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Neutrophil Cytosolic Factor 4 (NCF4)
NCF; P40PHOX; SH3PXD4; Neutrophil NADPH Oxidase Factor 4
Neutrophil cytosol factor 4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPA328Hu01 Recombinant Neutrophil Cytosolic Factor 4 (NCF4) In Stock
Antibodies PAA328Hu01 Polyclonal Antibody to Neutrophil Cytosolic Factor 4 (NCF4) In Stock
MAA328Hu21 Monoclonal Antibody to Neutrophil Cytosolic Factor 4 (NCF4) Customize
Assay Kits SEA328Hu ELISA Kit for Neutrophil Cytosolic Factor 4 (NCF4) Customize
SCA328Hu CLIA Kit for Neutrophil Cytosolic Factor 4 (NCF4) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPA328Mu01 Recombinant Neutrophil Cytosolic Factor 4 (NCF4) In Stock
Antibodies PAA328Mu01 Polyclonal Antibody to Neutrophil Cytosolic Factor 4 (NCF4) In Stock
MAA328Mu21 Monoclonal Antibody to Neutrophil Cytosolic Factor 4 (NCF4) Customize
Assay Kits SEA328Mu ELISA Kit for Neutrophil Cytosolic Factor 4 (NCF4) Customize
SCA328Mu CLIA Kit for Neutrophil Cytosolic Factor 4 (NCF4) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPA328Ra01 Recombinant Neutrophil Cytosolic Factor 4 (NCF4) Customize
Antibodies PAA328Ra01 Polyclonal Antibody to Neutrophil Cytosolic Factor 4 (NCF4) Customize
MAA328Ra21 Monoclonal Antibody to Neutrophil Cytosolic Factor 4 (NCF4) Customize
Assay Kits SEA328Ra ELISA Kit for Neutrophil Cytosolic Factor 4 (NCF4) Customize
SCA328Ra CLIA Kit for Neutrophil Cytosolic Factor 4 (NCF4) Customize