Oligosaccharyltransferase Complex Subunit (OSTC)
DC2; Hydrophobic protein HSF-28; Oligosaccharyltransferase complex subunit OSTC
The enzyme that catalyzes this process is a heteromeric, multisubunit membrane complex, called oligosaccharyltransferase () . Purification of OST from yeast and genetic methods identified nine proteins. Five of them, Wbp1, Swp1, Stt3, Ost1, and Ost2, are essential for viability of the cell, whereas Ost4, Ost5, Ost3, and Ost6 are not essential but are required for maximal OST activity. The specific function of the various subunits and the organization in the complex is largely enigmatic. Subunits Ost3 and Ost6 are alternatively present in the yeast OST complex; they modify the transfer specificity toward protein to be glycosylated and they specify the interaction with different translocation complexes. In mammals, two OST complexes exist that contain either one of two isoforms of Stt3, which display tissue-specific expression.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Oligosaccharyltransferase Complex Subunit (OSTC) Recombinant Protein Customized Service Offer
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- Customized Service n/a Polyclonal Antibody to Oligosaccharyltransferase Complex Subunit (OSTC) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Oligosaccharyltransferase Complex Subunit (OSTC) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Oligosaccharyltransferase Complex Subunit (OSTC) ELISA Kit Customized Service Offer