Orthodenticle Homeobox Protein 2 (OTX2)

MCOPS5
Orthodenticle Homeobox Protein 2 (OTX2)
OTX2 encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.Otx2 deficiency converted differentiating photoreceptor cells to amacrine-like neurons, reflecting a change in progenitor cell fate, and led to a total lack of pinealocytes in the pineal gland. Expression studies suggested that Otx2 is a direct upstream regulator of another cone-rod homeobox-containing gene, Crx, via binding to specific consensus sequences in the Crx promoter.
Organism species: Homo sapiens (Human)
  • Protein RPJ994Hu01Recombinant Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • AntibodyPAJ994Hu01Polyclonal Antibody to Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • AntibodyMAJ994Hu21Monoclonal Antibody to Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • Assay KitSEJ994HuELISA Kit for Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • Assay KitSCJ994HuCLIA Kit for Orthodenticle Homeobox Protein 2 (OTX2)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPJ994Mu01Recombinant Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • AntibodyPAJ994Mu01Polyclonal Antibody to Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • AntibodyMAJ994Mu21Monoclonal Antibody to Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • Assay KitSEJ994MuELISA Kit for Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • Assay KitSCJ994MuCLIA Kit for Orthodenticle Homeobox Protein 2 (OTX2)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPJ994Ra01Recombinant Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • AntibodyPAJ994Ra01Polyclonal Antibody to Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • AntibodyMAJ994Ra21Monoclonal Antibody to Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • Assay KitSEJ994RaELISA Kit for Orthodenticle Homeobox Protein 2 (OTX2)Customize
  • Assay KitSCJ994RaCLIA Kit for Orthodenticle Homeobox Protein 2 (OTX2)Customize
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