PDZ Binding Kinase (PBK)

SPK; Nori-3; TOPK; CT84; Spermatogenesis-related protein kinase; T-LAK Cell-Originated Protein Kinase; Lymphokine-activated killer T-cell-originated protein kinase
PDZ Binding Kinase (PBK)
PDZ Binding Kinase is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.
The variants differ at their 5-prime ends and encode the same protein, a deduced 322-amino acid serine/threonine kinase with a calculated molecular mass of 37.4 kD. Northern blot analysis of 12 human tissues detected transcripts of 1.9 and 2 kb in testis only. RT-PCR detected TOPK in activated, but not deactivated, T-LAK cells.
Organism species: Homo sapiens (Human)
  • Protein RPH436Hu01Recombinant PDZ Binding Kinase (PBK)Customize
  • AntibodyPAH436Hu01Polyclonal Antibody to PDZ Binding Kinase (PBK)Customize
  • AntibodyMAH436Hu21Monoclonal Antibody to PDZ Binding Kinase (PBK)Customize
  • Assay KitSEH436HuELISA Kit for PDZ Binding Kinase (PBK)Customize
  • Assay KitSCH436HuCLIA Kit for PDZ Binding Kinase (PBK)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPH436Mu01Recombinant PDZ Binding Kinase (PBK)Customize
  • AntibodyPAH436Mu01Polyclonal Antibody to PDZ Binding Kinase (PBK)Customize
  • AntibodyMAH436Mu21Monoclonal Antibody to PDZ Binding Kinase (PBK)Customize
  • Assay KitSEH436MuELISA Kit for PDZ Binding Kinase (PBK)Customize
  • Assay KitSCH436MuCLIA Kit for PDZ Binding Kinase (PBK)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPH436Ra01Recombinant PDZ Binding Kinase (PBK)Customize
  • AntibodyPAH436Ra01Polyclonal Antibody to PDZ Binding Kinase (PBK)Customize
  • AntibodyMAH436Ra21Monoclonal Antibody to PDZ Binding Kinase (PBK)Customize
  • Assay KitSEH436RaELISA Kit for PDZ Binding Kinase (PBK)Customize
  • Assay KitSCH436RaCLIA Kit for PDZ Binding Kinase (PBK)Customize
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