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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
PHD Finger Protein 21A (PHF21A)
BHC80 is a component of a BRAF35/histone deacetylase (HDAC) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS).The deduced 635-amino acid protein contains a PHD-type zinc finger. RT-PCR ELISA detected intermediate expression in all tissues and specific brain regions examined. The 634-amino acid BHC80 protein contains an N-terminal leucine zipper, a PHD zinc-finger domain most similar to that of the MI2 protein, and a C-terminal leucine zipper. RT-PCR detected tissue-specific expression, with the highest level in brain. In contrast to BRAF35, overexpression of transfected BHC80 in human embryonic kidney cells completely abrogated RE1-dependent transcriptional repression.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPN350Hu01 Recombinant PHD Finger Protein 21A (PHF21A) Customize
Antibodies PAN350Hu01 Polyclonal Antibody to PHD Finger Protein 21A (PHF21A) Customize
MAN350Hu21 Monoclonal Antibody to PHD Finger Protein 21A (PHF21A) Customize
Assay Kits SEN350Hu ELISA Kit for PHD Finger Protein 21A (PHF21A) Customize
SCN350Hu CLIA Kit for PHD Finger Protein 21A (PHF21A) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPN350Mu01 Recombinant PHD Finger Protein 21A (PHF21A) Customize
Antibodies PAN350Mu01 Polyclonal Antibody to PHD Finger Protein 21A (PHF21A) Customize
MAN350Mu21 Monoclonal Antibody to PHD Finger Protein 21A (PHF21A) Customize
Assay Kits SEN350Mu ELISA Kit for PHD Finger Protein 21A (PHF21A) Customize
SCN350Mu CLIA Kit for PHD Finger Protein 21A (PHF21A) Customize