POU Domain Class 6 Transcription Factor 2 (POU6F2)

RPF-1; Retina-Derived POU-Domain Factor-1
POU Domain Class 6 Transcription Factor 2 (POU6F2)
POU6F2 encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.POU6F2 gene contains at least 10 exons and encompasses over 125 kb. Sequence analysis revealed 4 positions at which alternate splicing occurs, potentially generating multiple transcripts.
Organism species: Homo sapiens (Human)
  • Protein RPM053Hu01Recombinant POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • AntibodyPAM053Hu01Polyclonal Antibody to POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • AntibodyMAM053Hu21Monoclonal Antibody to POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • Assay KitSEM053HuELISA Kit for POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • Assay KitSCM053HuCLIA Kit for POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPM053Mu01Recombinant POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • AntibodyPAM053Mu01Polyclonal Antibody to POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • AntibodyMAM053Mu21Monoclonal Antibody to POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • Assay KitSEM053MuELISA Kit for POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • Assay KitSCM053MuCLIA Kit for POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPM053Ra01Recombinant POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • AntibodyPAM053Ra01Polyclonal Antibody to POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • AntibodyMAM053Ra21Monoclonal Antibody to POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • Assay KitSEM053RaELISA Kit for POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
  • Assay KitSCM053RaCLIA Kit for POU Domain Class 6 Transcription Factor 2 (POU6F2)Customize
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