PQ Loop Repeat Containing Protein 1 (PQLC1)

PQLC1 Contains 2 PQ-loop domains. PQ-loop repeat family, a novel family of membrane proteins from Arabidopsis thaliana. The family consists of six members (AtPQL1-6) all predicted to contain seven transmembrane segments and two copies of the PQ-loop domain. The repeated PQ-loop domain is a well conserved feature present in several eukaryotic proteins. Although most PQ-loop repeat proteins are of unknown function some have been characterised from non-plant species. CTNS - a lysosomal cystine transporter from humans, STM1 - a putative G-protein coupled receptor from Schizosaccharomyces pombe, ERS1 - a Saccharomyces cerevisiae protein isolated as a suppressor of a trafficking mutant and LEC35/MPDU1 - an endoplasmic reticulum protein from mammals involved in the utilisation of dolichol monosaccharides during glycosylation.