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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
PR Domain Containing Protein 5 (PRDM5)
PFM2
PRDM5 is a recently identified family member that functions as a transcriptional repressor and behaves as a putative tumor suppressor in different types of cancer.  Overexpression of PRDM5 mRNA had opposite effects on the development of anterior neural structures, and resulted in embryos with a shorter body axis due to posterior truncation, a bigger head and abnormal somites. In situ hybridization experiments aimed at analyzing the integrity of wnt pathways during gastrulation at the level of the prechordal plate revealed inhibition of non canonical PCP wnt signaling in embryos overexpressing PRDM5, and over-activation of wnt/β-catenin signaling in embryos lacking Prdm5. PRDM5 regulates the expression of components of both canonical and non canonical wnt pathways and negatively modulates wnt signaling in vivo.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPS622Hu01 Recombinant PR Domain Containing Protein 5 (PRDM5) Customize
Antibodies PAS622Hu01 Polyclonal Antibody to PR Domain Containing Protein 5 (PRDM5) Customize
MAS622Hu21 Monoclonal Antibody to PR Domain Containing Protein 5 (PRDM5) Customize
Assay Kits SES622Hu ELISA Kit for PR Domain Containing Protein 5 (PRDM5) Customize
SCS622Hu CLIA Kit for PR Domain Containing Protein 5 (PRDM5) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPS622Mu01 Recombinant PR Domain Containing Protein 5 (PRDM5) Customize
Antibodies PAS622Mu01 Polyclonal Antibody to PR Domain Containing Protein 5 (PRDM5) Customize
MAS622Mu21 Monoclonal Antibody to PR Domain Containing Protein 5 (PRDM5) Customize
Assay Kits SES622Mu ELISA Kit for PR Domain Containing Protein 5 (PRDM5) Customize
SCS622Mu CLIA Kit for PR Domain Containing Protein 5 (PRDM5) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPS622Ra01 Recombinant PR Domain Containing Protein 5 (PRDM5) Customize
Antibodies PAS622Ra01 Polyclonal Antibody to PR Domain Containing Protein 5 (PRDM5) Customize
MAS622Ra21 Monoclonal Antibody to PR Domain Containing Protein 5 (PRDM5) Customize
Assay Kits SES622Ra ELISA Kit for PR Domain Containing Protein 5 (PRDM5) Customize
SCS622Ra CLIA Kit for PR Domain Containing Protein 5 (PRDM5) Customize