Parkinson Disease Protein 2 (PARK2)

AR-JP; LPRS2; PDJ; PRKN; Parkin; Autosomal Recessive,Juvenile; E3 ubiquitin-protein ligase parkin
Parkinson Disease Protein 2 (PARK2)
Parkin is a proteinencoded by the PARK2 gene.The precise function of this protein is unknown; however, the protein is a component of a multiprotein E3 ubiquitin ligase complex which in turn is part of the ubiquitin-proteasome system that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause a familial form of Parkinson's disease known as autosomal recessive juvenile Parkinson disease.
PARK2 is the parkin gene that may cause a form of autosomal recessive juvenile Parkinson disease due to a mutation in the parkin protein. This form of genetic mutation may be one of the most common known genetic causes of early-onset Parkinson disease.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
  • Protein RPL060Mu01Recombinant Parkinson Disease Protein 2 (PARK2)Customize
  • AntibodyPAL060Mu01Polyclonal Antibody to Parkinson Disease Protein 2 (PARK2)Customize
  • AntibodyMAL060Mu21Monoclonal Antibody to Parkinson Disease Protein 2 (PARK2)Customize
  • Assay KitSEL060MuELISA Kit for Parkinson Disease Protein 2 (PARK2)Customize
  • Assay KitSCL060MuCLIA Kit for Parkinson Disease Protein 2 (PARK2)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPL060Ra01Recombinant Parkinson Disease Protein 2 (PARK2)Customize
  • AntibodyPAL060Ra01Polyclonal Antibody to Parkinson Disease Protein 2 (PARK2)Customize
  • AntibodyMAL060Ra21Monoclonal Antibody to Parkinson Disease Protein 2 (PARK2)Customize
  • Assay KitSEL060RaELISA Kit for Parkinson Disease Protein 2 (PARK2)Customize
  • Assay KitSCL060RaCLIA Kit for Parkinson Disease Protein 2 (PARK2)Customize
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