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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Partner And Localizer Of BRCA2 (PALB2)
FANCN; Fanconi Anemia,Complementation Group N
PALB2 encodes a protein that functions in genome maintenance (double strand break repair). This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.
PALB2 was recently identified as a susceptibility gene for familial pancreatic cancer by scientists at the Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins. This paves for the way for developing a new "gene test" for families where pancreatic cancer occurs in multiple family members.Biallelic mutations in PALB2 (also known as FANCN), similar to biallelic BRCA2 mutations, cause Fanconi anemia.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPL983Hu01 Recombinant Partner And Localizer Of BRCA2 (PALB2) Customize
Antibodies PAL983Hu01 Polyclonal Antibody to Partner And Localizer Of BRCA2 (PALB2) Customize
MAL983Hu21 Monoclonal Antibody to Partner And Localizer Of BRCA2 (PALB2) Customize
Assay Kits SEL983Hu ELISA Kit for Partner And Localizer Of BRCA2 (PALB2) Customize
SCL983Hu CLIA Kit for Partner And Localizer Of BRCA2 (PALB2) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPL983Mu01 Recombinant Partner And Localizer Of BRCA2 (PALB2) Customize
Antibodies PAL983Mu01 Polyclonal Antibody to Partner And Localizer Of BRCA2 (PALB2) Customize
MAL983Mu21 Monoclonal Antibody to Partner And Localizer Of BRCA2 (PALB2) Customize
Assay Kits SEL983Mu ELISA Kit for Partner And Localizer Of BRCA2 (PALB2) Customize
SCL983Mu CLIA Kit for Partner And Localizer Of BRCA2 (PALB2) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPL983Ra01 Recombinant Partner And Localizer Of BRCA2 (PALB2) Customize
Antibodies PAL983Ra01 Polyclonal Antibody to Partner And Localizer Of BRCA2 (PALB2) Customize
MAL983Ra21 Monoclonal Antibody to Partner And Localizer Of BRCA2 (PALB2) Customize
Assay Kits SEL983Ra ELISA Kit for Partner And Localizer Of BRCA2 (PALB2) Customize
SCL983Ra CLIA Kit for Partner And Localizer Of BRCA2 (PALB2) Customize