Phosphatase And Actin Regulator 1 (PHACTR1)

RPEL1; RPEL Repeat Containing 1
Phosphatase And Actin Regulator 1 (PHACTR1)
The PHACTR proteins share highest similarity in sequences surrounding the N- and C-terminal RPEL repeats and in the C-terminal actin- and PP1-binding domains. In situ hybridization of rat brain showed enrichment of Phactr1 in cerebral cortex, hippocampus, olfactory tubercle, nucleus accumbens, caudate-putamen, and piriform cortex.
Endogenous PP1 coprecipitated with ectopically expressed rat Phactr1 in human embryonic kidney cells. Phactr1 also coprecipitated with actin in rat brain lysates. Yeast 2-hybrid analysis of a series of Phactr1 C-terminal truncation mutants indicated that PP1 bound to Phactr1 near the C terminus, while actin bound in a region containing RPEL repeats 2 and 3.
Organism species: Homo sapiens (Human)
  • Protein RPF743Hu01Recombinant Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • AntibodyPAF743Hu01Polyclonal Antibody to Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • AntibodyMAF743Hu21Monoclonal Antibody to Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • Assay KitSEF743HuELISA Kit for Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • Assay KitSCF743HuCLIA Kit for Phosphatase And Actin Regulator 1 (PHACTR1)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPF743Mu01Recombinant Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • AntibodyPAF743Mu01Polyclonal Antibody to Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • AntibodyMAF743Mu21Monoclonal Antibody to Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • Assay KitSEF743MuELISA Kit for Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • Assay KitSCF743MuCLIA Kit for Phosphatase And Actin Regulator 1 (PHACTR1)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPF743Ra01Recombinant Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • AntibodyPAF743Ra01Polyclonal Antibody to Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • AntibodyMAF743Ra21Monoclonal Antibody to Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • Assay KitSEF743RaELISA Kit for Phosphatase And Actin Regulator 1 (PHACTR1)Customize
  • Assay KitSCF743RaCLIA Kit for Phosphatase And Actin Regulator 1 (PHACTR1)Customize
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