Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)

HYP; HPDR; PEX; HPDR1; HYP1; XLH; Metalloendopeptidase homolog PEX; Vitamin D-resistant hypophosphatemic rickets protein; X-linked hypophosphatemia protein

Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)
PHEX is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets.
The PHEX protein is predicted to have a 20-residue N-terminal cytoplasmic tail, a 27-residue transmembrane domain, and a 702-residue extracellular C-terminal region. The protein belongs to the type II integral membrane zinc-dependent endopeptidase family. PHEX transcripts were identified in human osteosarcoma-derived cells and in differentiated mouse osteoblasts, but not in immature mouse preosteoblasts, indicating stage-specific expression.

Organism species: Homo sapiens (Human)

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Organism species: Mus musculus (Mouse)

  • Customized Service n/a Recombinant Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) Recombinant Protein Customized Service Offer
  • Customized Service n/a Monoclonal Antibody to Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) Monoclonal Antibody Customized Service Offer
  • Customized Service n/a Polyclonal Antibody to Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) Polyclonal Antibody Customized Service Offer
  • Customized Service n/a CLIA Kit for Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) CLIA Kit Customized Service Offer
  • Customized Service n/a ELISA Kit for Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

  • Customized Service n/a Recombinant Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) Recombinant Protein Customized Service Offer
  • Customized Service n/a Monoclonal Antibody to Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) Monoclonal Antibody Customized Service Offer
  • Customized Service n/a Polyclonal Antibody to Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) Polyclonal Antibody Customized Service Offer
  • Customized Service n/a CLIA Kit for Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) CLIA Kit Customized Service Offer
  • Customized Service n/a ELISA Kit for Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) ELISA Kit Customized Service Offer