Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)

HYP; HPDR; PEX; HPDR1; HYP1; XLH; Metalloendopeptidase homolog PEX; Vitamin D-resistant hypophosphatemic rickets protein; X-linked hypophosphatemia protein
Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)
PHEX is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets.
The PHEX protein is predicted to have a 20-residue N-terminal cytoplasmic tail, a 27-residue transmembrane domain, and a 702-residue extracellular C-terminal region. The protein belongs to the type II integral membrane zinc-dependent endopeptidase family. PHEX transcripts were identified in human osteosarcoma-derived cells and in differentiated mouse osteoblasts, but not in immature mouse preosteoblasts, indicating stage-specific expression.
Organism species: Homo sapiens (Human)
  • Protein RPP800Hu01Recombinant Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • AntibodyPAP800Hu01Polyclonal Antibody to Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • AntibodyMAP800Hu21Monoclonal Antibody to Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • Assay KitSEP800HuELISA Kit for Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • Assay KitSCP800HuCLIA Kit for Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPP800Mu01Recombinant Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • AntibodyPAP800Mu01Polyclonal Antibody to Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • AntibodyMAP800Mu21Monoclonal Antibody to Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • Assay KitSEP800MuELISA Kit for Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • Assay KitSCP800MuCLIA Kit for Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPP800Ra01Recombinant Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • AntibodyPAP800Ra01Polyclonal Antibody to Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • AntibodyMAP800Ra21Monoclonal Antibody to Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • Assay KitSEP800RaELISA Kit for Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
  • Assay KitSCP800RaCLIA Kit for Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX)Customize
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