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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Phosphoinositide Dependent Protein Kinase 1 (PDPK1)
PDK1; PkB-Like 1
PDPK1 is a master kinase, which is crucial for the activation of AKT/PKB and many other AGC kinases including PKC, S6K, SGK. An important role for PDPK1 is in the signalling pathways activated by several growth factors and hormones including insulin signalling. Mice lacking PDPK1 die during early embryonic development, indicating that this enzyme is critical for transmitting the growth-promoting signals nescessary for normal mammalian development.
Mice that are deficient in PDPK1 have a ≈40% decrease in body mass, mild glucose intolerance, and are resitant to cancer brought about by hyperactivation of the PI3K pathway (PTEN +/-).The structure of PDPK1 can be divided into two domains; the kinase or catalytic domain and the PH domain.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPC246Hu01 Recombinant Phosphoinositide Dependent Protein Kinase 1 (PDPK1) In Stock
Antibodies PAC246Hu01 Polyclonal Antibody to Phosphoinositide Dependent Protein Kinase 1 (PDPK1) In Stock
MAC246Hu21 Monoclonal Antibody to Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
Assay Kits SEC246Hu ELISA Kit for Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
SCC246Hu CLIA Kit for Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPC246Mu01 Recombinant Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
RPC246Mu02 Recombinant Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
Antibodies PAC246Mu01 Polyclonal Antibody to Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
PAC246Mu02 Polyclonal Antibody to Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
MAC246Mu21 Monoclonal Antibody to Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
Assay Kits SEC246Mu ELISA Kit for Phosphoinositide Dependent Protein Kinase 1 (PDPK1) In Stock
SCC246Mu CLIA Kit for Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPC246Ra01 Recombinant Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
Antibodies PAC246Ra01 Polyclonal Antibody to Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
MAC246Ra21 Monoclonal Antibody to Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
Assay Kits SEC246Ra ELISA Kit for Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize
SCC246Ra CLIA Kit for Phosphoinositide Dependent Protein Kinase 1 (PDPK1) Customize