Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)

GPAT; PRAT; ATase; Amidophosphoribosyltransferase; Glutamine phosphoribosylpyrophosphate amidotransferase
Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)
Amidophosphoribosyltransferase is an enzyme that converts phosphoribosylpyrophosphate (PRPP) into 5-phosphoribosylamine. The enzyme uses the ammonia group from the glutamine side-chain. This is the committing step in de novo purine synthesis.
Avian GPAT and AIRC were found to be divergently transcribed from a bidirectional promoter with distinct transcriptional start sites 229 bp apart. This was said to be the first example of bidirectional transcription of tightly linked genes that are not structurally related but are involved in the same pathway. The term dioskourion  was suggested to describe this eukaryotic transcriptional unit, which could be the eukaryotic equivalent of a prokaryotic operon.
Organism species: Homo sapiens (Human)
  • Protein RPH336Hu01Recombinant Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • AntibodyPAH336Hu01Polyclonal Antibody to Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • AntibodyMAH336Hu21Monoclonal Antibody to Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • Assay KitSEH336HuELISA Kit for Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • Assay KitSCH336HuCLIA Kit for Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPH336Mu01Recombinant Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • AntibodyPAH336Mu01Polyclonal Antibody to Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • AntibodyMAH336Mu21Monoclonal Antibody to Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • Assay KitSEH336MuELISA Kit for Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • Assay KitSCH336MuCLIA Kit for Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPH336Ra01Recombinant Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • AntibodyPAH336Ra01Polyclonal Antibody to Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • AntibodyMAH336Ra21Monoclonal Antibody to Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • Assay KitSEH336RaELISA Kit for Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
  • Assay KitSCH336RaCLIA Kit for Phosphoribosyl Pyrophosphate Amidotransferase (PPAT)Customize
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