Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)
LOT1; ZAC; ZAC1; Zinc finger protein PLAGL1; Lost on transformation 1; Tumor suppressor ZAC
PLAGL1 encodes a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate. Many transcript variants encoding two different isoforms have been found for this gene.The deduced 667-amino acid protein contains 7 C2H2 zinc fingers in its N-terminal half. Northern blot analysis of several mouse tissues detected highest Zac1 expression in pituitary.Rat and human LOT1 share 67.7% amino acid identity overall, with 85.5% identity in the N-terminal zinc finger region. Northern blot analysis detected multiple LOT1 transcripts in all human tissues examined, including spleen, thymus, prostate, testis, ovary, intestine, colon, and leukocytes. Highest expression was detected in ovary.
Organism species: Homo sapiens (Human)
- Recombinant protein RPH380Hu01 Recombinant Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) In Stock
- Polyclonal antibody PAH380Hu01 Polyclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) In Stock
- Labelled antibody LAH380Hu71 Biotin-Linked Polyclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) In Stock
- Monoclonal antibody MAH380Hu21 Monoclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) In Stock
- Sandwich ELISA SEH380Hu ELISA Kit for Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPH380Mu01 Recombinant Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) In Stock
- Customized Service n/a Monoclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPH380Ra01 Recombinant Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) In Stock
- Customized Service n/a Monoclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1) ELISA Kit Customized Service Offer