Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)

LOT1; ZAC; ZAC1; Zinc finger protein PLAGL1; Lost on transformation 1; Tumor suppressor ZAC
Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)
PLAGL1 encodes a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate. Many transcript variants encoding two different isoforms have been found for this gene.The deduced 667-amino acid protein contains 7 C2H2 zinc fingers in its N-terminal half. Northern blot analysis of several mouse tissues detected highest Zac1 expression in pituitary.Rat and human LOT1 share 67.7% amino acid identity overall, with 85.5% identity in the N-terminal zinc finger region. Northern blot analysis detected multiple LOT1 transcripts in all human tissues examined, including spleen, thymus, prostate, testis, ovary, intestine, colon, and leukocytes. Highest expression was detected in ovary.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
  • Protein RPH380Mu01Recombinant Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)Customize
  • AntibodyPAH380Mu01Polyclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)Customize
  • AntibodyMAH380Mu21Monoclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)Customize
  • Assay KitSEH380MuELISA Kit for Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)Customize
  • Assay KitSCH380MuCLIA Kit for Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPH380Ra01Recombinant Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)Customize
  • AntibodyPAH380Ra01Polyclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)Customize
  • AntibodyMAH380Ra21Monoclonal Antibody to Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)Customize
  • Assay KitSEH380RaELISA Kit for Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)Customize
  • Assay KitSCH380RaCLIA Kit for Pleiomorphic Adenoma Gene Like Protein 1 (PLAGL1)Customize
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