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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Post GPI Attachment To Proteins 2 (PGAP2)
FRAG1; CWH43-N; FGF Receptor Activating Protein 1; Cell Wall Biogenesis 43 N-Terminal Homolog
Biosynthesis of glycosylphosphatidylinositol-anchored proteins in the ER has been extensively studied, whereas the molecular events during the transport of GPI-APs from the ER to the cell surface are poorly understood. PGAP2 encoded a Golgi/ER-resident membrane protein. The low surface expression of GPI-APs was due to their secretion into the culture medium. GPI-APs were modified/cleaved by two reaction steps in the mutant cells. First, the GPI anchor was converted to lyso-GPI before exiting the trans-Golgi network. Second, lyso-GPI-APs were cleaved by a phospholipase D after transport to the plasma membrane.PGAP2 deficiency caused transport to the cell surface of lyso-GPI-APs that were sensitive to a phospholipase D. PGAP2 is involved in the processing of GPI-APs required for their stable expression at the cell surface.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPQ630Hu01 Recombinant Post GPI Attachment To Proteins 2 (PGAP2) Customize
Antibodies PAQ630Hu01 Polyclonal Antibody to Post GPI Attachment To Proteins 2 (PGAP2) Customize
MAQ630Hu21 Monoclonal Antibody to Post GPI Attachment To Proteins 2 (PGAP2) Customize
Assay Kits SEQ630Hu ELISA Kit for Post GPI Attachment To Proteins 2 (PGAP2) Customize
SCQ630Hu CLIA Kit for Post GPI Attachment To Proteins 2 (PGAP2) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPQ630Mu01 Recombinant Post GPI Attachment To Proteins 2 (PGAP2) Customize
Antibodies PAQ630Mu01 Polyclonal Antibody to Post GPI Attachment To Proteins 2 (PGAP2) Customize
MAQ630Mu21 Monoclonal Antibody to Post GPI Attachment To Proteins 2 (PGAP2) Customize
Assay Kits SEQ630Mu ELISA Kit for Post GPI Attachment To Proteins 2 (PGAP2) Customize
SCQ630Mu CLIA Kit for Post GPI Attachment To Proteins 2 (PGAP2) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPQ630Ra01 Recombinant Post GPI Attachment To Proteins 2 (PGAP2) Customize
Antibodies PAQ630Ra01 Polyclonal Antibody to Post GPI Attachment To Proteins 2 (PGAP2) Customize
MAQ630Ra21 Monoclonal Antibody to Post GPI Attachment To Proteins 2 (PGAP2) Customize
Assay Kits SEQ630Ra ELISA Kit for Post GPI Attachment To Proteins 2 (PGAP2) Customize
SCQ630Ra CLIA Kit for Post GPI Attachment To Proteins 2 (PGAP2) Customize