Potassium Channel Tetramerisation Domain Containing Protein 17 (KCTD17)

Potassium Channel Tetramerisation Domain Containing Protein 17 (KCTD17)
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. (potassium channel tetramerisation domain containing 17) is a 321 amino acid protein that contains one BTB domain, suggesting a possible role as a transcriptional regulator. The gene encoding KCTD17 maps to chromosome 22, which contains over 500 genes. As the second smallest human chromosome, 22 contains a surprising variety of interesting genes, including Phelan-McDermid syndrome, neurofibromatosis type 2 and autism.

Organism species: Homo sapiens (Human)

Organism species: Mus musculus (Mouse)

Organism species: Rattus norvegicus (Rat)