Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11)
Kir6.2; BIR; IKATP; Inward rectifier K(+) channel Kir6.2; ATP-sensitive inward rectifier potassium channel 11
KCNJ11 is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Potassium Inwardly Rectifying Channel Subfamily J, Member 11 (KCNJ11) ELISA Kit Customized Service Offer