Prolactin Regulatory Element Binding Protein (PREB)

SEC12; Mammalian guanine nucleotide exchange factor mSec12
Prolactin Regulatory Element Binding Protein (PREB)
PREB may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand.The deduced 417-amino acid protein, which is 89% identical to the rat protein, has 3 conserved WD repeats and 2 conserved pro-gln-rich regions. RNA dot blot analysis detected variable expression of PREB in all adult and fetal tissues. They proposed that PREB is a DNA-binding factor during mammalian development and that abnormal dosage may play a role in some of the phenotypic abnormalities observed in the partial trisomy 2p syndrome, which is characterized by a number of congenital defects, including genital abnormalities.
Organism species: Homo sapiens (Human)
  • Protein RPH321Hu01Recombinant Prolactin Regulatory Element Binding Protein (PREB)Customize
  • AntibodyPAH321Hu01Polyclonal Antibody to Prolactin Regulatory Element Binding Protein (PREB)Customize
  • AntibodyMAH321Hu21Monoclonal Antibody to Prolactin Regulatory Element Binding Protein (PREB)Customize
  • Assay KitSEH321HuELISA Kit for Prolactin Regulatory Element Binding Protein (PREB)Customize
  • Assay KitSCH321HuCLIA Kit for Prolactin Regulatory Element Binding Protein (PREB)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPH321Mu01Recombinant Prolactin Regulatory Element Binding Protein (PREB)Customize
  • AntibodyPAH321Mu01Polyclonal Antibody to Prolactin Regulatory Element Binding Protein (PREB)Customize
  • AntibodyMAH321Mu21Monoclonal Antibody to Prolactin Regulatory Element Binding Protein (PREB)Customize
  • Assay KitSEH321MuELISA Kit for Prolactin Regulatory Element Binding Protein (PREB)Customize
  • Assay KitSCH321MuCLIA Kit for Prolactin Regulatory Element Binding Protein (PREB)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPH321Ra01Recombinant Prolactin Regulatory Element Binding Protein (PREB)Customize
  • AntibodyPAH321Ra01Polyclonal Antibody to Prolactin Regulatory Element Binding Protein (PREB)Customize
  • AntibodyMAH321Ra21Monoclonal Antibody to Prolactin Regulatory Element Binding Protein (PREB)Customize
  • Assay KitSEH321RaELISA Kit for Prolactin Regulatory Element Binding Protein (PREB)Customize
  • Assay KitSCH321RaCLIA Kit for Prolactin Regulatory Element Binding Protein (PREB)Customize
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