R3H Domain Containing Like Protein (R3HDML)

Peptidase inhibitor R3HDML; Cysteine-rich secretory protein R3HDML;

R3H Domain Containing Like Protein (R3HDML)
A conserved sequence motif, the R3H domain has been identified in over 100 proteins and is suggested to be involved in polynucleotide-binding, including DNA, RNA and single-stranded DNA. R3HDML (R3H domain containing-like) is a 253 amino acid cysteine-rich secretory protein belonging to the CRISP family. Considered a putative serine protease inhibitor, is encoded by a gene located on human chromosome 20, which contains nearly 63 million bases and encodes over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes that are thought to be important for seminal production and may be potential targets for male contraception.

Organism species: Homo sapiens (Human)

Organism species: Mus musculus (Mouse)