RNA Binding Motif Protein 47 (RBM47)

RBM47, Contains 3 RRM (RNA recognition motif) domains. rbm47, a novel RNA binding protein, regulates zebrafish head development. Rbm47 is a novel RNA-binding protein critical for head formation and embryonic patterning during zebrafish embryogenesis which may act through a Wnt8a signaling pathway. Vertebrate trunk induction requires inhibition of bone morphogenetic protein (BMP) signaling, whereas vertebrate head induction requires concerted inhibition of both Wnt and BMP signaling. RNA binding proteins play diverse roles in embryonic development and their roles in vertebrate head development remain to be elucidated.