RAB Interacting Lysosomal Protein Like Protein 1 (RILPL1)
RLP1
RILPL1 Does not regulate lysosomal morphology and distribution. Belongs to the RILPL family. 3 isoforms of the human protein are produced by alternative splicing.
Rab7 and Rab34 are implicated in regulation of lysosomal morphology and they share a common effector referred to as the RILP (Rab-interacting lysosomal protein). Two novel proteins related to RILP were identified and are tentatively referred to as RLP1 and RLP2 (for RILP-like protein 1 and 2, respectively). Overexpression of RILP caused enlarged lysosomes that are positioned more centrally in the cell.The molecular basis for the effect of RILP on lysosomes was investigated, leading to the demonstration that a 62-residue region (amino acids 272-333) of RILP is necessary for RILP's role in regulating lysosomal morphology.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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- Customized Service n/a Polyclonal Antibody to RAB Interacting Lysosomal Protein Like Protein 1 (RILPL1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for RAB Interacting Lysosomal Protein Like Protein 1 (RILPL1) CLIA Kit Customized Service Offer
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant RAB Interacting Lysosomal Protein Like Protein 1 (RILPL1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to RAB Interacting Lysosomal Protein Like Protein 1 (RILPL1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to RAB Interacting Lysosomal Protein Like Protein 1 (RILPL1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for RAB Interacting Lysosomal Protein Like Protein 1 (RILPL1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for RAB Interacting Lysosomal Protein Like Protein 1 (RILPL1) ELISA Kit Customized Service Offer