Recombination Activating Gene 2 (RAG2)

Recombination Activating Gene 2 (RAG2)
RAG2 encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4.
Organism species: Homo sapiens (Human)
  • Protein RPH267Hu01Recombinant Recombination Activating Gene 2 (RAG2)Customize
  • AntibodyPAH267Hu01Polyclonal Antibody to Recombination Activating Gene 2 (RAG2)Customize
  • AntibodyMAH267Hu21Monoclonal Antibody to Recombination Activating Gene 2 (RAG2)Customize
  • Assay KitSEH267HuELISA Kit for Recombination Activating Gene 2 (RAG2)Customize
  • Assay KitSCH267HuCLIA Kit for Recombination Activating Gene 2 (RAG2)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPH267Mu01Recombinant Recombination Activating Gene 2 (RAG2)Customize
  • AntibodyPAH267Mu01Polyclonal Antibody to Recombination Activating Gene 2 (RAG2)Customize
  • AntibodyMAH267Mu21Monoclonal Antibody to Recombination Activating Gene 2 (RAG2)Customize
  • Assay KitSEH267MuELISA Kit for Recombination Activating Gene 2 (RAG2)Customize
  • Assay KitSCH267MuCLIA Kit for Recombination Activating Gene 2 (RAG2)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPH267Ra01Recombinant Recombination Activating Gene 2 (RAG2)Customize
  • AntibodyPAH267Ra01Polyclonal Antibody to Recombination Activating Gene 2 (RAG2)Customize
  • AntibodyMAH267Ra21Monoclonal Antibody to Recombination Activating Gene 2 (RAG2)Customize
  • Assay KitSEH267RaELISA Kit for Recombination Activating Gene 2 (RAG2)Customize
  • Assay KitSCH267RaCLIA Kit for Recombination Activating Gene 2 (RAG2)Customize
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