Renal Tumor Antigen (RAGE)
MOK; RAGE1; MAPK/MAK/MRK Overlapping Kinase
Tumor antigens recognized by cytolytic T cells (CTLs) can be classified into 4 groups: shared tumor-specific antigens encoded by MAGE-type genes that are silent in most normal tissues except testis and expressed in many tumors; differentiation antigens that are also expressed in normal cells; antigens resulting from tumor-specific point mutations; and antigens overexpressed in tumor cells. By screening cells expressing both HLA-B7 and kidney tumor cell RNA with autologous CTLs, followed by anchored PCR analysis, Gaugler et al. (1996) isolated a cDNA encoding RAGE. RT-PCR analysis detected expression only in retina and in a number of tumor cell types. One putative RAGE open reading frame encodes a 40-amino acid protein and includes the peptide recognized by HLA-B7-restricted CTLs.
Organism species: Homo sapiens (Human)
- Recombinant protein RPH266Hu01 Recombinant Renal Tumor Antigen (RAGE) In Stock
- Polyclonal antibody PAH266Hu01 Polyclonal Antibody to Renal Tumor Antigen (RAGE) In Stock
- Monoclonal antibody MAH266Hu21 Monoclonal Antibody to Renal Tumor Antigen (RAGE) In Stock
- Sandwich ELISA SEH266Hu ELISA Kit for Renal Tumor Antigen (RAGE) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPH266Mu01 Recombinant Renal Tumor Antigen (RAGE) In Stock
- Polyclonal antibody PAH266Mu01 Polyclonal Antibody to Renal Tumor Antigen (RAGE) In Stock
- Customized Service n/a CLIA Kit for Renal Tumor Antigen (RAGE) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Renal Tumor Antigen (RAGE) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPH266Ra01 Recombinant Renal Tumor Antigen (RAGE) In Stock
- Monoclonal antibody MAH266Ra21 Monoclonal Antibody to Renal Tumor Antigen (RAGE) In Stock
- Polyclonal antibody PAH266Ra01 Polyclonal Antibody to Renal Tumor Antigen (RAGE) In Stock
- Sandwich ELISA SEH266Ra ELISA Kit for Renal Tumor Antigen (RAGE) In Stock