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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Retinitis Pigmentosa GTPase Regulator (RPGR)
CRD; COD1; CORDX1; PCDX; RP15; RP3; XLRP3; Orf15; Retinitis Pigmentosa 15; Cone Dystrophy 1(X-Linked)
RPGR encodes a protein with a series of six RCC1-like domains, characteristic of the highly conserved guanine nucleotide exchange factors. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.The predicted 90-kD RPGR protein contains in its N-terminal half a tandem repeat structure highly similar to the regulator of chromosome condensation (RCC1), which regulates the GTPase RAN. The C terminus of the protein contains a cluster of basic residues followed by a consensus isoprenylation site. The authors noted that confirmation of the isoprenylation of this site would establish a novel means of membrane anchorage for a GTPase regulator.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPF777Hu01 Recombinant Retinitis Pigmentosa GTPase Regulator (RPGR) Customize
Antibodies PAF777Hu01 Polyclonal Antibody to Retinitis Pigmentosa GTPase Regulator (RPGR) Customize
MAF777Hu21 Monoclonal Antibody to Retinitis Pigmentosa GTPase Regulator (RPGR) Customize
Assay Kits SEF777Hu ELISA Kit for Retinitis Pigmentosa GTPase Regulator (RPGR) Customize
SCF777Hu CLIA Kit for Retinitis Pigmentosa GTPase Regulator (RPGR) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPF777Mu01 Recombinant Retinitis Pigmentosa GTPase Regulator (RPGR) Customize
Antibodies PAF777Mu01 Polyclonal Antibody to Retinitis Pigmentosa GTPase Regulator (RPGR) Customize
MAF777Mu21 Monoclonal Antibody to Retinitis Pigmentosa GTPase Regulator (RPGR) Customize
Assay Kits SEF777Mu ELISA Kit for Retinitis Pigmentosa GTPase Regulator (RPGR) Customize
SCF777Mu CLIA Kit for Retinitis Pigmentosa GTPase Regulator (RPGR) Customize