Retinoic Acid Early Transcript 1E (RAET1E)

LETAL; ULBP4; NKG2DL4; N2DL4; RL-4; NKG2D ligand 4; Lymphocyte effector toxicity activation ligand; RAE-1-like transcript 4

Retinoic Acid Early Transcript 1E (RAET1E)
Members of the RAET1 family, such as RAET1E, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E and RAET1G differ from the other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences.
The deduced 263-amino acid protein contains alpha-1 and alpha-2 domains, a transmembrane domain, and a short cytoplasmic tail. Real-time RT-PCR detected highest expression in skin, with much lower expression in trachea and trace levels in other tissues.

Organism species: Homo sapiens (Human)

Organism species: Mus musculus (Mouse)