Ribosomal L24 Domain Containing Protein 1 (RSL24D1)

RSL24D1 encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals.

Yeast Rlp24 was involved in biogenesis of the early pre-60S ribonucleoparticle. Rlp24 associated with the pre-60S particle in the nucleolus and maintained this association following export of pre-60S to the cytoplasm. Depletion of Rlp24 resulted in an unstable complex.