Ribosomal Protein S29 (RPS29)

RPS29 encodes a ribosomal protein that is a component of the 40S subunit and a member of the S14P family of ribosomal proteins. The protein, which contains a C2-C2 zinc finger-like domain that can bind to zinc, can enhance the tumor suppressor activity of Ras-related protein 1A (KREV1). It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

The deduced 56-amino acid human RPS29 is identical to rat Rps29. Northern blot analysis suggested variable expression of RPS29 in colorectal cancers compared to adjacent normal tissues, although no correlation between the level of expression and the severity of the disease was found.