Ripply 2 Homolog (RIPPLY2)

The deduced 128-amino acid protein contains a WRPW tetrapeptide near its N terminus and a conserved domain of about 50 amino acids found in other Ripply proteins. In zebrafish embryos, Ripply2 was expressed in the paraxial mesoderm and was subsequently confined to the presomitic mesoderm.

The deduced 151-amino acid protein contains a WRPW tetrapeptide near its N terminus and a conserved domain of about 50 amino acids found in other Ripply proteins. In zebrafish embryos, Ripply1 was expressed in the anterior presomitic mesoderm and in several newly formed somites. The expression pattern, highest in anterior presomitic mesoderm and gradually decreasing in a posterior-to-anterior direction in somites like a ripple, suggested the designation of this gene.