SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1)
HARP; HHARP; HepA-Related Protein; ATP-Driven Annealing Helicase; Sucrose nonfermenting protein 2-like 1
SMARCAL1 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. HARP bound with higher affinity to forked DNA than to single-stranded DNA (sDNA) or double-stranded DNA (dsDNA). HARP had ATPase activity that was stimulated by forked DNA, and to a lesser extent by ssDNA and dsDNA.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like Protein (SMARCAL1) ELISA Kit Customized Service Offer