SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily D, Member 2 (SMARCD2)

SMARCD2 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein.

BAF60b encodes a polypeptide of 475 amino acids and is homologous to the yeast SWP73 gene, a component of the yeast SWI/SNF chromatin remodeling complex. The human genes BAF60a, BAF60b, and BAF60c are highly homologous.