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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Serine/Threonine Kinase 11 (STK11)
LKB1; PJS; Polarization-Related Protein LKB1; Peutz-Jeghers Syndrome
LKB1 is a primary upstream kinase of adenine monophosphate-activated protein kinase (AMPK), a necessary element in cell metabolism that is required for maintaining energy homeostasis. It is now clear that LKB1 exerts its growth suppressing effects by activating a group of other ~14 kinases, comprising AMPK and AMPK-related kinases. Activation of AMPK by LKB1 suppresses growth and proliferation when energy and nutrient levels are scarce. Activation of AMPK-related kinases by LKB1 plays vital roles maintaining cell polarity thereby inhibiting inappropriate expansion of tumour cells. A picture from current research is emerging that loss of LKB1 leads to disorganization of cell polarity and facilitates tumour growth under energetically unfavorable conditions.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPH115Hu01 Recombinant Serine/Threonine Kinase 11 (STK11) Customize
Antibodies PAH115Hu01 Polyclonal Antibody to Serine/Threonine Kinase 11 (STK11) Customize
MAH115Hu21 Monoclonal Antibody to Serine/Threonine Kinase 11 (STK11) Customize
Assay Kits SEH115Hu ELISA Kit for Serine/Threonine Kinase 11 (STK11) Customize
SCH115Hu CLIA Kit for Serine/Threonine Kinase 11 (STK11) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPH115Mu01 Recombinant Serine/Threonine Kinase 11 (STK11) Customize
RPH115Mu02 Recombinant Serine/Threonine Kinase 11 (STK11) Customize
Antibodies PAH115Mu01 Polyclonal Antibody to Serine/Threonine Kinase 11 (STK11) Customize
PAH115Mu02 Polyclonal Antibody to Serine/Threonine Kinase 11 (STK11) Customize
MAH115Mu21 Monoclonal Antibody to Serine/Threonine Kinase 11 (STK11) Customize
Assay Kits SEH115Mu ELISA Kit for Serine/Threonine Kinase 11 (STK11) In Stock
SCH115Mu CLIA Kit for Serine/Threonine Kinase 11 (STK11) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPH115Ra01 Recombinant Serine/Threonine Kinase 11 (STK11) Customize
Antibodies PAH115Ra01 Polyclonal Antibody to Serine/Threonine Kinase 11 (STK11) Customize
MAH115Ra21 Monoclonal Antibody to Serine/Threonine Kinase 11 (STK11) Customize
Assay Kits SEH115Ra ELISA Kit for Serine/Threonine Kinase 11 (STK11) Customize
SCH115Ra CLIA Kit for Serine/Threonine Kinase 11 (STK11) Customize