Short Chain Dehydrogenase/Reductase Family 42E, Member 1 (SDR42E1)

Short Chain Dehydrogenase/Reductase Family 42E, Member 1 (SDR42E1)
SDR42E1Belongs to the 3-beta-HSD family, is a 393 amino acid multi-pass membrane protein that belongs to the 3-β-HSD family.
The gene encoding SDR42E1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn’s disease, which is a gastrointestinal inflammatory condition. The putative HSD-1 and EAK-7 mammalian orthologs Sdr42e1 and KIAA1609 may be components of this input.

Organism species: Homo sapiens (Human)

Organism species: Mus musculus (Mouse)

Organism species: Rattus norvegicus (Rat)