Sirtuin 6 (SIRT6)
SIR2L6; Silent Mating Type Information Regulation 2 Homolog 6; Mono-ADP-Ribosyltransferase Sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2-like protein 6
SIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.Sirtuins can be divided into 4 main classes in eukaryotes based on amino acid sequence motifs, with yeast Sir2 belonging to class Ia. The deduced 355-amino acid SIRT6 protein is a class IV sirtuin, a class not present in prokaryotes.
Organism species: Homo sapiens (Human)
- Recombinant protein RPE916Hu01 Recombinant Sirtuin 6 (SIRT6) In Stock
- Recombinant protein RPE916Hu02 Recombinant Sirtuin 6 (SIRT6) In Stock
- Polyclonal antibody PAE916Hu01 Polyclonal Antibody to Sirtuin 6 (SIRT6) In Stock
- Labelled antibody LAE916Hu71 Biotin-Linked Polyclonal Antibody to Sirtuin 6 (SIRT6) In Stock
- Labelled antibody LAE916Hu81 FITC-Linked Polyclonal Antibody to Sirtuin 6 (SIRT6) In Stock
- Monoclonal antibody MAE916Hu21 Monoclonal Antibody to Sirtuin 6 (SIRT6) In Stock
- Sandwich ELISA SEE916Hu ELISA Kit for Sirtuin 6 (SIRT6) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPE916Mu01 Recombinant Sirtuin 6 (SIRT6) In Stock
- Recombinant protein RPE916Mu02 Recombinant Sirtuin 6 (SIRT6) In Stock
- Polyclonal antibody PAE916Mu01 Polyclonal Antibody to Sirtuin 6 (SIRT6) In Stock
- Labelled antibody LAE916Mu71 Biotin-Linked Polyclonal Antibody to Sirtuin 6 (SIRT6) In Stock
- Polyclonal antibody PAE916Mu02 Polyclonal Antibody to Sirtuin 6 (SIRT6) In Stock
- Sandwich ELISA SEE916Mu ELISA Kit for Sirtuin 6 (SIRT6) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPE916Ra01 Recombinant Sirtuin 6 (SIRT6) In Stock
- Polyclonal antibody PAE916Ra01 Polyclonal Antibody to Sirtuin 6 (SIRT6) In Stock
- Labelled antibody LAE916Ra71 Biotin-Linked Polyclonal Antibody to Sirtuin 6 (SIRT6) In Stock
- Customized Service n/a CLIA Kit for Sirtuin 6 (SIRT6) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Sirtuin 6 (SIRT6) ELISA Kit Customized Service Offer