Solute Carrier Family 38, Member 6 (SLC38A6)

NAT-1; SNAT6; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 6; Probable sodium-coupled neutral amino acid transporter 6

Solute Carrier Family 38, Member 6 (SLC38A6)
SLC38A6 mRNA was detected only in cells with a stromal distribution suggesting immune lineage. SLC1A5 mRNA was expressed primarily in LE/sGE and stromal cells, and it was more abundant in uteri of pregnant ewes. Furthermore, P4 induced and IFNT further stimulated SLC1A5 expression in LE/sGE. Endometrial SLC1A1, SLC7A5, and SLC43A2 mRNAs demonstrated both temporal and cellSLCspecific changes. Several mRNAs were detectable in trophectoderm, while others were more abundant in endoderm of conceptuses. These results document coordinate changes in expression of transporters that are likely responsible for increases in amounts of neutral and acidic amino acids in the uterine lumen to support conceptus growth, development, and survival.

Organism species: Homo sapiens (Human)

Organism species: Mus musculus (Mouse)

Organism species: Rattus norvegicus (Rat)