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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1)
OATP-C; LST-1; OATPC; OATP1B1; OATP2; SLC21A6; Solute Carrier Family 21 Member 6; Organic Anion Transporting Polypeptide C
SLCO1B1 encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. The SLC21A6 gene encodes a deduced 691-amino acid protein containing 12 transmembrane domains, 7 putative N-glycosylation sites in the extracellular loops, and 2 potential phosphorylation sites. Northern blot analysis detected major 3.0- and minor 4.8-kb SLC21A6 transcripts exclusively in liver, in contrast to the more widely expressed SLC21A3.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPE517Hu01 Recombinant Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Customize
Antibodies PAE517Hu01 Polyclonal Antibody to Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Customize
MAE517Hu21 Monoclonal Antibody to Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Customize
Assay Kits SEE517Hu ELISA Kit for Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Customize
SCE517Hu CLIA Kit for Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Customize