Spermatogenesis Associated Protein 7 (SPATA7)

HSD3; Spermatogenesis-associated protein HSD3
Spermatogenesis Associated Protein 7 (SPATA7)
SPATA7 encodes a 599-amino acid protein containing several DNA-binding sites and 3 phosphorylation sites. The human and rat SPATA7 proteins share 77% sequence identity. Northern blot analysis of rat tissues showed testis-specific expression, which was first detected at postnatal day 30. Immunohistochemistry of rat testis localized SPATA7 to primary spermatocytes in early prophase of meiosis I.
Mutation analysis in additional patients revealed homozygosity for the same R108X mutation in a Dutch LCA patient as well as a frameshift mutation in another LCA patient of Middle Eastern origin; homozygosity for different nonsense and frameshift mutations in SPATA7 was also identified in 2 patients with juvenile retinitis pigmentosa.
Organism species: Homo sapiens (Human)
  • Protein RPN552Hu01Recombinant Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • AntibodyPAN552Hu01Polyclonal Antibody to Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • AntibodyMAN552Hu21Monoclonal Antibody to Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • Assay KitSEN552HuELISA Kit for Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • Assay KitSCN552HuCLIA Kit for Spermatogenesis Associated Protein 7 (SPATA7)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPN552Mu01Recombinant Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • AntibodyPAN552Mu01Polyclonal Antibody to Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • AntibodyMAN552Mu21Monoclonal Antibody to Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • Assay KitSEN552MuELISA Kit for Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • Assay KitSCN552MuCLIA Kit for Spermatogenesis Associated Protein 7 (SPATA7)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPN552Ra01Recombinant Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • AntibodyPAN552Ra01Polyclonal Antibody to Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • AntibodyMAN552Ra21Monoclonal Antibody to Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • Assay KitSEN552RaELISA Kit for Spermatogenesis Associated Protein 7 (SPATA7)Customize
  • Assay KitSCN552RaCLIA Kit for Spermatogenesis Associated Protein 7 (SPATA7)Customize
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