Spermidine/Spermine N1-Acetyl Transferase Like Protein 1 (SATL1)

SATL1, Belongs to the acetyltransferase family,Contains 1 N-acetyltransferase domain. Acetyltransferase (or transacetylase) is a type of transferase enzyme that transfers an acetyl group. N-acetyltransferase is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.

Spermidine/spermine N1- acetyltransferase (SSAT) appears to have a role in the determination of tumor sensitivity to a new class of antineoplastic agents. The further study of SSAT and the associated polyamine metabolism should provide a better understanding of the regulation and function of these cations.