Sulfatase 1 (SULF1)
HSULF-1; Extracellular sulfatase Sulf-1
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
The deduced 871-amino acid protein contains an N-terminal signal sequence, followed by a sulfatase domain, a hydrophilic region, and a C-terminal substrate recognition domain. It also has a coiled-coil region, 10 N-glycosylation sites, and several consensus furin cleavage sites. SULF1 shares about 64% identity with SULF2 and 93% identity with mouse Sulf1.
Organism species: Homo sapiens (Human)
- Recombinant protein RPH108Hu01 Recombinant Sulfatase 1 (SULF1) In Stock
- Polyclonal antibody PAH108Hu01 Polyclonal Antibody to Sulfatase 1 (SULF1) In Stock
- Monoclonal antibody MAH108Hu21 Monoclonal Antibody to Sulfatase 1 (SULF1) In Stock
- Sandwich ELISA SEH108Hu ELISA Kit for Sulfatase 1 (SULF1) In Stock
- Sandwich CLIA SCH108Hu CLIA Kit for Sulfatase 1 (SULF1) In Stock
Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Sulfatase 1 (SULF1) Recombinant Protein Customized Service Offer
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- Customized Service n/a Polyclonal Antibody to Sulfatase 1 (SULF1) Polyclonal Antibody Customized Service Offer
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- Customized Service n/a ELISA Kit for Sulfatase 1 (SULF1) ELISA Kit Customized Service Offer