Suppressors Of Cytokine Signaling 1 (SOCS1)

CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP3; JAK-binding protein; STAT-induced STAT inhibitor 1; Tec-interacting protein 3
Suppressors Of Cytokine Signaling 1 (SOCS1)
SOCS1 orthologs have been identified in several mammals for which complete genome data are available.This SOCS1 encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
  • Protein RPH158Mu01Recombinant Suppressors Of Cytokine Signaling 1 (SOCS1)Customize
  • AntibodyPAH158Mu01Polyclonal Antibody to Suppressors Of Cytokine Signaling 1 (SOCS1)Customize
  • AntibodyMAH158Mu21Monoclonal Antibody to Suppressors Of Cytokine Signaling 1 (SOCS1)Customize
  • Assay KitSEH158MuELISA Kit for Suppressors Of Cytokine Signaling 1 (SOCS1)Customize
  • Assay KitSCH158MuCLIA Kit for Suppressors Of Cytokine Signaling 1 (SOCS1)Customize
Organism species: Rattus norvegicus (Rat)
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