Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)

RASA1; RASA5; SYNGAP; Ras/Rap GTPase-activating protein SynGAP; Neuronal RasGAP
Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)
SYNGAP1 is a ras GTPase-activating protein that is critical for cognition and synapse function. Mutations in humans cause mental retardation.
Several mutations in the SYNGAP1 gene were identified as the cause of mental retardation. Mental retardation is sometimes associated with syndromes of other defects caused by the same gene, but SYNGAP1-associated mental retardation is not; it is therefore called non-syndromic mental retardation. Since neither of the parents of children with this condition have the mutation, this means it was a sporadic mutation that occurred during division of the parents' gametes (meiosis) or fertilization of the egg. It is a dominant mutation, which means that the individual will be retarded if only one allele is mutated.
Organism species: Homo sapiens (Human)
  • Protein RPE286Hu01Recombinant Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • AntibodyPAE286Hu01Polyclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • AntibodyMAE286Hu21Monoclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • Assay KitSEE286HuELISA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • Assay KitSCE286HuCLIA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPE286Mu01Recombinant Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • AntibodyPAE286Mu01Polyclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • AntibodyMAE286Mu21Monoclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • Assay KitSEE286MuELISA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • Assay KitSCE286MuCLIA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPE286Ra01Recombinant Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • AntibodyPAE286Ra01Polyclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • AntibodyMAE286Ra21Monoclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • Assay KitSEE286RaELISA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
  • Assay KitSCE286RaCLIA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)Customize
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