Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)

RASA1; RASA5; SYNGAP; Ras/Rap GTPase-activating protein SynGAP; Neuronal RasGAP

Synaptic Ras GTPase Activating Protein 1 (SYNGAP1)
SYNGAP1 is a ras GTPase-activating protein that is critical for cognition and synapse function. Mutations in humans cause mental retardation.
Several mutations in the SYNGAP1 gene were identified as the cause of mental retardation. Mental retardation is sometimes associated with syndromes of other defects caused by the same gene, but SYNGAP1-associated mental retardation is not; it is therefore called non-syndromic mental retardation. Since neither of the parents of children with this condition have the mutation, this means it was a sporadic mutation that occurred during division of the parents' gametes (meiosis) or fertilization of the egg. It is a dominant mutation, which means that the individual will be retarded if only one allele is mutated.

Organism species: Homo sapiens (Human)

  • Customized Service n/a Recombinant Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) Recombinant Protein Customized Service Offer
  • Customized Service n/a Monoclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) Monoclonal Antibody Customized Service Offer
  • Customized Service n/a Polyclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) Polyclonal Antibody Customized Service Offer
  • Customized Service n/a CLIA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) CLIA Kit Customized Service Offer
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Organism species: Mus musculus (Mouse)

  • Customized Service n/a Recombinant Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) Recombinant Protein Customized Service Offer
  • Customized Service n/a Monoclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) Monoclonal Antibody Customized Service Offer
  • Customized Service n/a Polyclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) Polyclonal Antibody Customized Service Offer
  • Customized Service n/a CLIA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) CLIA Kit Customized Service Offer
  • Customized Service n/a ELISA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

  • Customized Service n/a Recombinant Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) Recombinant Protein Customized Service Offer
  • Customized Service n/a Monoclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) Monoclonal Antibody Customized Service Offer
  • Customized Service n/a Polyclonal Antibody to Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) Polyclonal Antibody Customized Service Offer
  • Customized Service n/a CLIA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) CLIA Kit Customized Service Offer
  • Customized Service n/a ELISA Kit for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) ELISA Kit Customized Service Offer