TBC1 Domain Family, Member 3C (TBC1D3C)

TBC1 Domain Family, Member 3C (TBC1D3C)
By genomic sequence analysis, Hodzic et al. (2006) identified 8 paralogs of the TBC1D3 gene on chromosome 17, including TBC1D3C, which they called paralog B. All TBC1D3 paralogs encode a deduced 549-amino acid protein, but missense changes at 6 residues among the paralogs result in 5 different TBC1D3 isoforms. The TBC1D3 paralogs appeared to be differentially expressed in human tissues.The TBC1D3 paralogs appeared to be differentially expressed in human tissues. TBC1D3 was the only paralog expressed in heart.
By genomic sequence analysis, Hodzic et al. (2006) identified 8 TBC1D3 paralogs, including the TBC1D3C gene, on chromosome 17q12. The paralogs are clustered in 2 groups of 4 genes, and each cluster spans approximately 400 kb.

Organism species: Homo sapiens (Human)