TBC1 Domain Family, Member 3G (TBC1D3G)

TBC1 Domain Family, Member 3G (TBC1D3G)
By genomic sequence analysis, Hodzic et al. (2006) identified 8 paralogs of the TBC1D3 gene on chromosome 17, including TBC1D3G, which they called paralog D.
All TBC1D3 paralogs encode a deduced 549-amino acid protein, but missense changes at 6 residues among the paralogs result in 5 different TBC1D3 isoforms. The TBC1D3G and TBC1D3H genes encode identical proteins. The TBC1D3 paralogs appeared to be differentially expressed in human tissues.
By genomic sequence analysis, Hodzic et al. (2006) identified 8 TBC1D3 paralogs, including the TBC1D3G gene, on chromosome 17q12. The paralogs are clustered in 2 groups of 4 genes, and each cluster spans approximately 400 kb.

Organism species: Homo sapiens (Human)