TEA Domain Family, Member 2 (TEAD2)

Jacquemin et al. (1996) cloned the mouse and human homologs of TEF4, a member of the TEA/ATTS transcription factor family. They found that a partial TEF4 cDNA encodes a protein that is 67% identical to TEF1 (189967). Additionally, they observed that TEF4 can cooperatively bind the GT-IIC and Sph(I+II) enhansons of the SV40 enhancer. Jacquemin et al. (1996) determined by RT-PCR that human TEF4 is strongly expressed in a human ovarian carcinoma cell line, and they determined by in situ hybridization that tef4 is differentially expressed during mouse embryonic development.

By fluorescence in situ hybridization and radiation hybrid analysis, Jacquemin et al. (1999) mapped the TEAD2 gene to 19q13.3.